The hidden dangers of caffeine: How coffee causes exhaustion, fatigue and addiction
When you consume caffeine, the drug begins its effects by initiating uncontrolled neuron firing in your brain, according to Stephen Cherniske in his book, Caffeine Blues. This excess neuron activity triggers your pituitary gland to secrete a hormone that tells your adrenal glands to produce adrenalin.
via The hidden dangers of caffeine: How coffee causes exhaustion, fatigue and addiction.